Instructions

This medicine is for use in the rectum or around the anus. DO NOT take this medicine by mouth.

Try to have a bowel movement just before using this medicine.

Follow the instructions on the package to use this medicine correctly.

Wash your hands before and after using this medicine. However, do not get up right away to wash your hands if you are supposed to lie down for a period of time to give the medicine time to work.

Lie on your left side, with your right knee bent toward your chest. Or, you may kneel on both knees, with your arms folded on the floor with your head resting on your arms.

Unwrap the suppository and moisten it with a few drops of cool water. Insert the pointed end into the anus, and push it all the way in with your finger.

If the suppository becomes soft, you can make it firmer by refrigerating it. You can run it under cold water if the suppository is wrapped.

If your dose is one-half (1/2) suppository, carefully cut it lengthwise using a clean, sharp knife.

If you have hemorrhoids, you may coat the tip of the suppository with a water-soluble lubricant (for example K-Y Jelly) before inserting. Do NOT use Vaseline.

Next, lie on your left side for at least 30 minutes, and keep the medicine in your rectum for at least 1 hour or, preferably, overnight.

Store at room temperature or in the refrigerator. Do not freeze.

Drink plenty of water while on this medicine.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

This medicine can make you sensitive to the sun. Use sunscreen or protective clothing when in sun.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Tell your doctor if symptoms do not get better or if they get worse.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

IMPORTANT: Children and teenagers should not use this medicine if they have cold and flu symptoms or chickenpox.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

Please check with your doctor before drinking alcohol while on this medicine.

This medicine passes into breast milk. Ask your doctor before breastfeeding.

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• diarrhea
• excess gas
• headaches
• nausea
• rectal burning or irritation
• stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• abdominal cramps
• bleeding from rectum
• chest pain
• severe, watery or bloody diarrhea
• fever
• swelling in the neck or throat
• signs of kidney damage (such as change in urine color or bubbly urine)
• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
• red, burning, or itchy skin
• shortness of breath
• blood in stool
• urinating less often

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.