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Impaired immune system

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Impaired immune system

The immune system is the body's natural defense system that helps fight infections. An impaired immune system does not work properly and can't effectively protect a person against infection.

Some conditions and medicines weaken or impair the immune system. These may include:

  • Substance use disorders or problems caused by quitting their use (withdrawal).
  • Certain diseases or conditions. Diabetes, cancer, HIV/AIDS, or conditions in which the body mistakenly identifies its own tissues as harmful (autoimmune disorders) are some examples.
  • Chemotherapy or radiation therapy.
  • Some medicines, such as corticosteroids or those taken to suppress the immune system after an organ transplant.
  • Surgery to remove the spleen (splenectomy).

Current as of: September 25, 2023

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
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This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

NOTICE: This health information was not created by Columbia University Irving Medical Center and may not necessarily reflect specific CUIMC practices. For medical advice to your personal condition, please consult your doctor. Medical advice disclaimer.